Correlación entre cociente proteína/creatinina y proteinuria en orina de 24 horas en pacientes embarazadas con sospecha de preeclampsia en el Hospital Regional Cd. Madero
Abstract
Preeclampsia is one of the frequent, serious complications of pregnancy; with a high fetal maternal morbidity and mortality; For this reason, it is important to find diagnostic tools that allow us to detect it and initiate appropriate treatments in a timely manner. proteinuria is one of the criteria that can be part of the diagnosis, but is not necessary when damage to a target organ is demonstrated. Among the diagnostic tests to detect proteinuria in urine is the 24-hour urine collection with the measurement of proteins greater than 300 mg; but currently other tests with less technical complexity have been found that can help diagnosis, such as the protein/creatinine index; which can help detect proteinuria in a single urine sample; Therefore, it is important to know if there is a good correlation between the two. The objective of this study was to determine the correlation between the protein/creatinine ratio and 24-hour urine proteinuria in pregnant patients with suspected preeclampsia at the Cd. Madero Regional Hospital. 24-hour urine protein and protein/creatinine ratio were analyzed in pregnant patients more than 20 weeks' gestation with blood pressure 140/90 mmHg or higher, in whom preeclampsia is suspected; with the collection is assessed in a study of correlation of quantitative variables in the NCSS system 11. From the assessment of 51 patients with suspected preeclampsia, a Pearson coefficient of 0.3279 with a p of 0.0188 (95% confidence interval) was obtained. 0.0566 – 0.5535). Whether there is a statistically significant correlation between the protein/creatinine ratio and 24-hour urine protein; with which the index could be used as a timely diagnostic test for suspicion of preeclampsia, reducing the technical difficulties of 24-hour urine collection.
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